FDA OKs Invivyd's COVID preventive Pemgarda for emergency use The pre-exposure treatment is indicated for adolescents and adults with moderate-to-severe immunocompromising conditions. CIDRAP

The Food and Drug Administration (FDA) on March 22 granted emergency use authorization (EUA) for Invivyd's monoclonal antibody to prevent COVID-19 in immunocompromised patients, which fills a gap following the withdrawal of Evusheld in January 2023.

New data show Paxlovid outperforms molnupiravir against severe COVID-19 outcomes A large study yesterday in the International Journal of Infectious Diseases shows that, if prescribed within 5 days of confirmed infection, Paxlovid (nirmatrelvir-ritonavir) is more effective in protecting against all-cause mortality and severe COVID-19 in adults than is molnupiravir, another antiviral drug. CIDRAP

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Flu linked to greater risk for neurological disorders than COVID-19, study shows - UPI.com The flu is more likely to lead to a neurological disorder than COVID-19, according to a new study that surprised its authors. UPI

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After four years with Covid-19, the US is settling into a new approach to respiratory virus season | CNN With the arrival of spring, the United States is easing out of respiratory virus season, a familiar pattern that has been challenged by Covid-19 for the past four years. Deidre McPhillips CNN

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Experts say that focused planning and forecasting efforts helped avoid some of the worst-case scenarios. But there was still a significant number of severe outcomes, and there are still key areas of improvement – especially around vaccination.

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Young and old: how the Covid pandemic has affected every UK generation From children behind on milestones to less active older people, broader effects are being felt four years after the initial outbreak The Guardian

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COVID-induced lung infection linked to heart damage Severe acute respiratory distress syndrome (ARDS) related to COVID-19 infections can damage the heart even when the virus itself doesn’t affect heart tissue. The findings come from a study today in Circulation. CIDRAP

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The study suggests that ARDS triggers widespread inflammation in the body, which leads to secondary cardiovascular complications.

4 years later, experts are just beginning to 'scratch the surface' of understanding long COVID Four years after the WHO declared the COVID-19 outbreak to be a pandemic, researchers say much is still not understood about a common complication: long COVID. ABC News ABC News

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Since the early days of the pandemic, scientists have learned a great deal about what puts someone at risk for long COVID, but researchers say we are still "scratching the surface" when it comes to our understanding of what causes the condition or how to treat it.

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